December 1, 2023

Can appetite suppressants help control your hunger and kickstart your weight loss? Or are they another scam perpetrated by the $33 billion weight loss industry [1]? This guide looks at the best appetite suppressants and what they’re most effective for; PhenQ is our pick for the best appetite suppressants overall.

Best Appetite Suppressants

The best appetite suppressants include:

  • PhenQ – Best appetite suppressant overall.
  • Instant Knockout – Best appetite suppressant for men.
  • Leanbean – Best appetite suppressant for low stimulants.
  • Zotrim – Best appetite suppressant for women.
  • Phen24 – Best appetite suppressant for hunger control and fat burning.
  • Trimtone – Best appetite suppressant and metabolism booster.
  • PrimeShred – Best appetite suppressant for exercise and endurance.

1. PhenQ – The Best Appetite Suppressants Overall – Ranking 4.9/5


  • Five-in-one solution formula.
  • Production facility meets Food and Drug Administration (FDA) standards.
  • Refund guarantee within 60 days.
  • Conveniently available without a prescription.
  • All orders are shipped for free.


  • Pricey.
  • Exclusively available via the official website only.
  • Possible adverse effects include nausea, vomiting, diarrhea, constipation and bloating.

Who Should Try PhenQ?

PhenQ, our top pick for the best appetite suppressants, is excellent for women and men looking for a healthy way to lose weight. Its five functions include assisting in fat burning, halting the formation of more fat, reducing hunger, increasing vitality and lifting spirits.

Who Shouldn’t Take PhenQ?

Even though it’s among the best appetite suppressants, do not take PhenQ if you are pregnant, nursing, under 18, or have any serious medical condition. Those already taking prescription drugs should speak with their doctor before taking PhenQ.

PhenQ Ranking: 4.9/5

Efficacy – 5/5

The benefits of PhenQ have been scientifically established, making it one of the best weight loss pills. According to testimonials, customers were able to lose the weight they had set out to do successfully.

Ingredient Safety – 5/5

PhenQ contains only natural, safe ingredients. These are some of them:

  • Chromium picolinate, a supplement that lessens food cravings [2].
  • The fat-binding properties of nopal allow for its excretion.
  • Caffeine anhydrous helps control the appetite hormone ghrelin.
  • Improved fat-to-energy conversion, thanks to L-carnitine fumarate.
  • Calorie-burning calcium carbonate.
  • a-Lacys Reset, a metabolic booster.
  • Capsimax, a powder that raises core body temperature.

Cost – 4.2/5

The one-month supply of PhenQ costs $69.95. If you buy two, you’ll get one free for $139.90. If you buy three bottles of PhenQ and pay $189.95, you’ll get two free bottles and a bottle of Advana Cleanse.

User Satisfaction – 4.7/5

Most customer reviewers have nothing but good things to say about the company’s products and services. When asked to rate PhenQ among the best appetite suppressants, 65% of consumers gave it a positive PhenQ review, while 29% gave it a negative review [3].


PhenQ is one of the best appetite suppressants for losing weight without the risk of side effects. Scientifically-proven ingredients are combined to produce a powerful hunger suppressant that supports moderate weight loss when combined with a nutritious diet and regular exercise.

>>Check the best prices for PhenQ

2. Instant Knockout – The Best Appetite Suppressants for Men – Ranking 4.8/5


  • Helps you eat less and aids in weight loss.
  • Produced in a lab that meets FDA standards.
  • Refunds are available within 30 days.
  • Subscriptions are available.


  • Difficulty sleeping, nausea, heartburn, bloating and diarrhea are all possible side effects.
  • Pills are large and cumbersome to swallow.
  • High dose of caffeine.

Who Should Try Instant Knockout?

Instant Knockout is one of the best appetite suppressants for men on our list. It is a great weight loss supplement for athletes who don’t want to sacrifice muscle mass. Instant Knockout was initially developed with mixed martial arts (MMA) competitors in mind. However, it can help any athlete looking to shed pounds and improve their athletic prowess.

Who Shouldn’t Take Instant Knockout?

This appetite suppressant is not ideal if you are pregnant or nursing, using theophylline to treat asthma, or taking beta-blockers for high blood pressure. Those sensitive to caffeine may want to look elsewhere for a weight loss pill since Instant Knockout contains quite a large dose.

Instant Knockout Ranking: 4.8/5

Efficacy – 5/5

Scientific studies have demonstrated that all nine active ingredients in Instant Knockout are some of the best appetite suppressants to help with weight loss. Customers have said they were successful in losing weight, naming it one of the best thermogenic fat burners.

Ingredient Safety – 4.5/5

Instant Knockout contains caffeine and glucomannan, which may lead to adverse reactions in certain users. Caffeine use is linked to sleep disruption and jitters, and glucomannan has been linked to gastrointestinal distress and diarrhea. Instant Knockout also contains these additional ingredients:

  • Green tea extract can aid in the oxidation of lipids, the reduction of belly fat accumulation, and the digestion of starches.
  • As a result of its role in metabolic regulation, vitamin B12 may help keep you from gaining excess weight.
  • L-Theanine may mitigate caffeine’s jitters and crash effects.
  • Vitamin D3 may positively affect body mass index and weight.
  • Vitamin B6 boosts dopamine and serotonin and makes it easier to follow healthy habits like dieting and exercising.
  • Cayenne pepper contains an active ingredient called capsaicin, a thermogenic agent. This means that it speeds up your metabolism and elevates your core temperature, all while burning more fat and giving you more energy [4].

Cost – 4.5/5

Instant Knockout Cut costs $65 for a supply lasting one month. You may save money on a four-month supply by purchasing only three bottles. You’ll also get free international delivery and access to the Boss Shred program (consisting of a video series and downloadable ebooks).

User Satisfaction – 4/5

Instant Knockout reviews are inconsistent. The best ones are unanimous in their assertion that Instant Knockout is an effective weight loss pill due to its high-quality ingredients. Most complaints focus on defective goods and unhelpful customer support [5].


Instant Knockout is one of the best appetite suppressants to help shed unwanted pounds while speeding up your metabolism. It was created with MMA fighters in mind, but anybody looking to trim down without sacrificing muscle may benefit from using it.

>>Check the best prices for Instant Knockout

3. Leanbean – Best Appetite Suppressant Supplements for Low Stimulants – Ranking 4.75/5


  • Outstanding client support.
  • More glucomannan content than rivals.
  • Low dose of stimulants.
  • Lowers hunger and food cravings.
  • You may get a full refund if you aren’t satisfied within 90 days.
  • Production facility meets FDA standards.


  • You’ll need to take it three times per day.
  • The time it takes to see results might be longer than that of the competition.
  • Stomach pain, diarrhea, gas and bloating are all possible adverse reactions.
  • The satisfaction guarantee only applies to purchases of a 90-day supply.

Who Should Try Leanbean?

Leanbean is a good choice for female athletes to reduce fat while keeping muscle mass. It is also the right solution for women struggling to control their desires for sweets, chocolate and carbohydrates. Leanbean is not only for women; it may also help reduce hunger in men. 

Since Leanbean does not include high doses of caffeine, it is the most effective appetite suppressor with low stimulants. It’s also suitable for vegan and vegetarian diets.

Who Shouldn’t Take Leanbean?

Avoid using Leanbean if you’re expecting a child or nursing a baby. In addition, diabetics, particularly those on insulin, are advised against it. If you suffer from irritable bowel syndrome or any digestive disorder, you should avoid Leanbean. Plus, Leanbean may not be ideal if you have a liver problem or are taking drugs processed in the liver.

Cyclosporine, Digoxin, Lithium carbonate, Levothyroxine and Warfarin are just a few examples of drugs you shouldn’t take with the supplement. We recommend talking to your doctor before using it if you have any pre-existing issues.

Leanbean Ranking: 4.75/5

Efficacy – 4.9/5

According to customer reviews, Leanbean effectively aids in fat loss while preserving lean muscle mass. While you may not experience weight loss due to the effects of exercise on muscle mass, you will notice a slimmer, more toned appearance.

Ingredient Safety – 4/5

If you take an excessive quantity of garcinia cambogia, it may cause harm to your liver. Glucomannan may give you gastrointestinal troubles such as diarrhea, nausea and gas until the body adapts to it. 

Never exceed the manufacturer-recommended dose without checking with a doctor first.

These are some of the additional ingredients:

  • Turmeric can help reduce BMI and overall weight [6].
  • Chromium picolinate, which helps keep insulin levels stable.
  • Vitamins B12 and B6 are known to increase stamina.
  • Green coffee beans may increase metabolic rate and normalize glucose levels [7].
  • Choline plays a vital role in maintaining a healthy fat metabolism.
  • The anti-inflammatory properties of acai berry aid in weight loss by reducing overall inflammation in the body.
  • Zinc aids in the breakdown of both carbs and fats in the body.
  • Piperine enhances the effectiveness of the other ingredients.

Cost – 4.5/5

Leanbean is available for $59.99 for 180 capsules, plus $7.95 delivery. Two bottles cost $119.98, but ordering three will get you a free bottle plus a free fitness guide and nutrition plan for $189.97.

User Satisfaction – 4.9/5

Responses from clients have been overwhelmingly favorable. Several users of Leanbean claim they still haven’t put back on the weight they lost.


Leanbean is one of the best appetite suppressants if you’re looking for a weight loss product with low stimulants. The product targets female users, but male users can still expect positive results.

>>Check the best prices for Leanbean

4. Zotrim – The Best Appetite Suppressants for Women – Ranking 4.7/5


  • Evidence from scientific studies shows that it works.
  • Guarantees your satisfaction or your money back for a full 100 days.
  • Helps you feel full for longer, which leads to fewer consumed calories. 
  • Creates a thermogenic effect to burn fat.


  • Causes possible harm to the kidneys and liver.
  • Nausea and skin rashes are some of the adverse reactions.
  • Dosage may not be potent enough for everyone.

Who Should Try Zotrim?

As one of the most potent appetite suppressant supplements, Zotrim was developed specifically with the needs of women in mind. Despite its targeted audience, men and women both might benefit from taking the strongest appetite suppressant, Zotrim.

Who Shouldn’t Take Zotrim? 

Those under the age of 18, pregnant, breastfeeding, or sensitive to caffeine should avoid Zotrim.

Zotrim Ranking: 4.7/5

Efficacy – 5/5

Zotrim’s combination of guarana, yerba maté and damiana helps people lose weight. It reduces hunger, makes them feel full for longer, and decreases their overall caloric intake. After six weeks, 22% of people lost a considerable amount of weight [8].

Ingredient Safety – 4.5/5

The substances in Zotrim have been the subject of significant research and are all proven to be risk-free. The  ingredients in Zotrim include:

  • Caffeine improves your alertness and energy levels, making it easier to exercise and supporting your efforts to lose weight. However, it may also produce feelings of jitteriness in some people.
  • Increased metabolic rate from guarana facilitates the release of fat cells into the circulation, which your body can use as fuel.
  • The mood-lifting properties of damiana may aid in controlling binge eating caused by stress or sadness.
  • Yerba maté first boosts your metabolism to burn more fat, then blocks the formation of new fat cells [9].
  • B vitamins, especially B3, help keep your metabolism running smoothly and reduce tiredness.

Cost – 4.5/5

The price of Zotrim for a month’s supply is $49.99. The 90-day supply costs $99.99, which is like receiving one bottle free. For $149.99, you can purchase a three-bottle supply good for 90 days, with the remaining two bottles discounted to zero cost.

User Satisfaction – 4.5/5

There is a consensus of approval among customers. More than two-thirds of Amazon reviewers who rated the strongest appetite suppressant Zotrim awarded it a perfect score of five stars. Only 17% awarded it only one or two stars.


When it comes to best appetite suppressants, Zotrim bills itself as “the most studied and most proven product available.” The assertion could be valid [9] since five studies and 10 articles support it.

>>Check the best prices for Zotrim

5. Phen24 – Best for Hunger Control and Fat Burning – Ranking 4.6/5


  • Guaranteed refund within 60 days.
  • Enhances the quality of sleep.
  • Metabolism-improving supplements can be used both during the day and at night.
  • Eases nerves and tension.


  • Lack of detail on ingredient amounts.
  • Optimal results may be achieved with proper diet and exercise.
  • Individuals who already suffer from a medical ailment are not eligible to utilize this product.

Who Should Try Phen24?

Phen24 is the best appetite suppressant for accelerating fat loss day and night. Try Phen24 if you have trouble losing weight, are stressed, or can’t go to sleep at night. It aids in cortisol regulation, leading to lower stress and anxiety levels and less emotional eating.

Who Shouldn’t Take Phen24?

You shouldn’t use Phen24 if you’re under 18, pregnant, nursing, struggling with depression, or using antidepressants. It is also not ideal if you have diabetes or cancer of the breast, testicles, or prostate. People who take medication for autoimmune or endocrine problems should also avoid it.

Phen24 Ranking: 4.6/5

Efficacy – 5/5

Most reviews about Phen24 have praised it as the strongest appetite suppressant that works. You may take these best appetite suppressants in the morning and evening to provide your metabolism with a constant boost.

Ingredient Safety – 4.5/5

Side effects from both the daytime diet tablets’ caffeine and the overnight bottle’s glucomannan are possible. In addition, the daytime ingredients include:

  • The nutrient iodine improves thyroid performance and facilitates weight loss.
  • Cayenne, which suppresses hunger, speeds up your metabolism and encourages more calorie expenditure [10].
  • The amino acid phenylalanine helps in the production of the fat-burning hormone dopamine.
  • Caffeine-rich guarana.
  • Manganese, which assists in blood sugar homeostasis and decreases inflammation.

Other ingredients for the evening include:

  • The insulin-balancing mineral chromium picolinate.
  • A metabolic stimulant, biotin.
  • Molybdenum, which eliminates waste products of metabolism.
  • Catechins, found in green tea extract, are potent antioxidants that also speed up your metabolism [11].
  • Choline bitartrate, an effective fat burner.
  • Essential to your metabolism’s health, vitamins B5 and B6.
  • The fat-burning properties of hops.

Cost – 4/5

One of the best appetite suppressants, Phen24, is also one of the most costly. One box costs $74.99, two boxes cost $149.99, and you get one free; three boxes cost $224.99, and two more are free.

User Satisfaction – 4/5

Some users of Phen24 have complained that it takes too long to see benefits, with many reporting a wait of two to three months. Phen24 supporters, on the other hand, are ecstatic about their increased vitality and the motivation they’ve found to hit the gym and whip up some healthy meals.


Because it increases your metabolism around the clock, you’ll burn fat even while you sleep, making Phen24 the most potent appetite suppressant pill available. It’s expensive and may take a while before you see weight loss results. However, the energy you feel after only a week or two may motivate you to make lifestyle changes that complement the diet pills’ effects.

>>Check the best prices for Phen24

6. Trimtone – Best Appetite Suppressant Pills and Metabolism Booster – Ranking 4.5/5


  • Suppresses hunger and raises metabolic rate.
  • Useful for fat burning.
  • 100-day cash-back assurance.


  • If you purchase two or more bottles, you will receive a money-back guarantee.
  • It’s not vegan or vegetarian-friendly.
  • Only orders of three or more bottles qualify for free delivery.

Who Should Try Trimtone?

Trimtone is one of the best appetite suppressants and best metabolism boosters designed explicitly for women since their bodies process fat differently than men. Aside from aiding in weight loss, it also helps improve memory, cardiovascular health, brain function and inflammatory levels. 

Who Shouldn’t Take Trimtone?

Avoid using Trimtone if you are a woman who is pregnant, nursing, or on any medicine.

Trimtone Ranking: 4.5/5

Efficacy – 5/5

Trimtone’s components are some of the best appetite suppressants, aiding with weight loss and a lower body mass index in clinical trials.

Ingredient Safety – 4.5/5

Taking Trimtone first thing in the morning might cause jitters due to the high caffeine content. Trimtone has less glucomannan than many rival products and is less likely to induce gastrointestinal distress. Additional ingredients are:

  • Grains of paradise, which can burn the visceral fat around your organs [12].
  • Green coffee bean extract includes chlorogenic acid, which aids in weight loss.
  • Capsaicinoids found in green tea may increase metabolic rate.
  • Caffeine anhydrous can speed up your metabolism.

Cost – 4.5/5

For $49.99, you can purchase enough Trimtone to last you a month; for $99.99, you can stock up for three months; and for $149.99, you can get enough to last you five months with a buy-two-get-one-free deal on the three bottles.

User Satisfaction – 4.5/5

Many ladies have seen significant weight loss, particularly in problem areas like the belly and thighs. For this reason, they have expressed their satisfaction with the product online.


Trimtone has developed one of the best appetite suppressants for women’s unique physiological needs. It’s a supplement that can help you lose weight when combined with a low-calorie diet and regular exercise, but it won’t work on its own.

>>Check the best prices for Trimtone

7. PrimeShred – Best for Appetite Suppressant for Exercise and Endurance – Ranking 4.4/5


  • Reduce fat stores rapidly.
  • Vegan and vegetarian-friendly.
  • Purchases of two or more bottles get free delivery.
  • Increased metabolic rate due to thermogenesis.
  • 100-day money-back guarantee.


  • Nausea, vomiting and elevated blood pressure are common adverse effects
  • You can only buy it on the website

Who Should Try PrimeShred?

PrimeShred is one of the most potent appetite-suppressant supplements. It targets males who want to reduce their overall body fat percentage while simultaneously boosting their levels of lean muscle mass. That said, females can give it a try as well.

PrimeShred is ideal for athletes looking to control their appetites without sacrificing muscular growth.

Who Shouldn’t Take PrimeShred?

You shouldn’t take PrimeShred if you’re pregnant, breastfeeding, or under 18.

PrimeShred Ranking: 4.4/5 

Efficacy – 5/5

There has been a lot of praise from satisfied customers, most of whom are male.

Ingredient Safety – 4/5

PrimeShred includes the nootropic DMEA, which may enhance mental clarity and energy. However, excessive use might be harmful, so it’s crucial to stick to the recommended dosage [13]. Aside from this, you’ll also need the following ingredients:

  • Rhodiola rosea, which boosts stamina and reduces abdominal fat.
  • L-Theanine helps reduce the amount of sugar and fat your body absorbs from food.
  • The inclusion of bioperine increases the efficacy of the other ingredients [14].
  • L-Tyrosine, which helps your attention and concentration.

Cost – 4.5/5

PrimeShred costs $49.99 + $7.95 for delivery for one bottle. You can get three bottles for $99.99 when you buy two and get one free or $149.99 when you buy three and get two free. Delivery is free when you buy two or more bottles.

User Satisfaction – 4.5/5

Male reviewers have praised PrimeShred for being one of the best appetite suppressants. Most of them have successfully reduced their body fat percentage without losing any of their muscle.


PrimeShred is one of the most potent appetite-suppressant supplements for male athletes. It is also ideal for those who want weight loss in pursuit of a super-shredded body, despite some cause for worry with the presence of DMEA.

>>Check the best prices for PrimeShred

The Best Appetite Suppressants: What Are They?

The best appetite suppressants aim to reduce hunger levels and facilitate weight loss.

Prescription appetite suppressants are limited in number. While there are a few products that have been authorized by the FDA to help curb appetite, there are dozens more that have not. The Food and Drug Administration has not approved any appetite suppressants for sale over the counter. 

Natural products are available online and in-store without a prescription to help you reduce your appetite, burn fat and lose weight.

Best Appetite Suppressants: How Do they Work for Weight Loss?

The best appetite suppressants to lose weight work in three ways:

  • Serotonin is a target of a wider variety of appetite-suppressing drugs. The “feel good” hormone serotonin causes the brain to register satiety even while hunger persists.
  • Other best appetite suppressants work by preventing the adrenal gland in the brain from signaling to the body that you are hungry. You won’t feel hungry since your body isn’t getting the message.
  • The most potent appetite suppressants contain a significant quantity of fiber, often derived from nopal or glucomannan. Fiber takes up space in your belly. For this reason, you will feel full after consuming a lesser quantity of food than you would normally.

Prescription Appetite Suppressants vs. OTC Appetite Suppressants

You’ve probably seen countless advertisements for the best appetite suppressant pills claiming to explain how to suppress appetite naturally, reduce cravings and help you burn fat faster. 

However, attempting to sort through the different brands, products, and ingredients to find a safe appetite suppressant can get even more complicated. This is especially when considering the FDA approval and prescription options.

Often, users may need help understanding what FDA approval means or why the FDA doesn’t approve some supplements. The FDA will only approve medications that are tested and proven to be safe appetite suppressants. Plus, these meds must meet federal safety and quality standards and provide benefits that outweigh potential risks.

>>Check the latest prices for PhenQ

Understanding Over-the-Counter Appetite Suppressants

Over-the-counter (OTC) best appetite suppressant pills are extracted from plants and sold as herbal supplements. The FDA doesn’t consider herbal supplements to be medications, so they don’t require approval to be sold legally. 

That doesn’t necessarily mean that dietary supplements or herbal appetite suppressants have more risks than FDA-approved prescription medication. It simply means that the supplements contain vitamins, minerals and botanical extracts that the FDA hasn’t tested for efficacy.

Doctors rarely prescribe prescription-grade appetite suppressants for their patients unless they meet specific qualifications, such as morbid obesity or a BMI over 27 coupled with a disorder like diabetes. While the FDA has approved several medications to enhance weight loss, each patient reacts differently to prescription medications and may experience side effects such as:

  • Insomnia
  • Dry-mouth
  • Constipation
  • Digestive discomfort
  • Nausea
  • Diarrhea
  • Stomach pain
  • High blood pressure
  • Increased heart rate
  • Anxiety
  • Headaches
  • Blurred vision

What Is a Safe Appetite Suppressant?

A safe appetite suppressant is a product designed to curb hunger and, in turn, help you lose weight. 

The FDA has approved these medications that you can only get with a doctor’s prescription:

  • Liraglutide (Saxenda), which you take an injection. It is also available as a diabetes treatment under the brand name Victoza. The drug dampens hunger by acting on a hormone in the gut.
  • Naltrexone/bupropion (Contrave) contains two medications and may affect the reward system in your brain. As a result, eating certain foods that would typically make you feel good no longer does. It also works on the hypothalamus, the part of your brain that regulates appetite, temperature and other functions.
  • Phentermine/topiramate (Qsymia) is a combination of two drugs. Phentermine is a stimulant that makes you feel less hungry. Topiramate is a medicine used for seizures and headaches, but as part of a combo with phentermine, it may make you feel less hungry and more full.
  • Other options include phentermine, benzphetamine, diethylpropion and phendimetrazine. However, you can only use those for up to 12 weeks.

Some supplements claim to be the best appetite suppressants. These products, though, aren’t classified as drugs by the FDA, so they’re not reviewed by the agency before they hit the market. The FDA doesn’t approve any over-the-counter safe appetite suppressant supplements.

Natural Safe Appetite Suppressants: What Are They?

Supplements, specific nutrients, teas and spices may also help with weight management. In fact, throughout history, people around the world have used these same naturally safe appetite suppressant ingredients for their positive metabolic effects.

Overeating (high-calorie intake) and its connection to obesity are one of the most complex and challenging issues in healthcare today. That’s where a naturally safe appetite suppressant can help.

There are many reasons why you might feel like you’re always hungry. Some include nutrient deficiencies, a lack of fiber or healthy fats in your diet, fatigue, or high emotional stress. However, it doesn’t have to be this way.

In addition to improving your diet and exercise habits, naturally safe appetite suppressant supplements can help you achieve satiety. Plus, they can reduce cravings and help you lose weight without the dangers of most diet pills.

What is the best thing to suppress your appetite? First and foremost, it’s essential to eat a healthy diet consistently, which makes you feel full.

>>Check the best prices for PhenQ

Why Did We Choose the Best Appetite Suppressants?

These best appetite suppressants on our list were selected because they are top performers in their respective fields. We examined a range of variables comparing these to other safe appetite suppressant pills, before picking our best selections.

Best Appetite Suppressants Ingredients Quality 

When selecting hunger suppressants for weight loss, we were careful only to consider those with premium ingredients. It’s safe to say that most of these vitamins and minerals are vegetarian-friendly and vegan. 

Some of these products are free of common allergens to accommodate those with food allergies, including soy, dairy and gluten. Some are entirely produced in the United States.

Best Appetite Suppressants Safe Formula

Each item we chose has a combination that’s safe for most healthy folks. 

Women who are pregnant or nursing, as well as minors, should avoid using the most potent appetite suppressant. Some people shouldn’t use supplements because they include caffeine, including those with stomach problems, liver concerns, or heart illnesses.

We prioritized supplements with low risks of side effects. For this reason, none of the ones we chose contained more caffeine than the FDA-recommended maximum of 400 mg per day.

Best Appetite Suppressants Ease of Use

All of our selected best appetite suppressants are straightforward to use. Leanbean is the most involved since you have to take two capsules three times a day. 

PrimeShred, on the other hand, calls for three morning tablets with a glass of water.

Best Appetite Suppressants Stimulant Quantity

When selecting the strongest appetite suppressant supplements, we looked for those that could curb hunger without relying too much on stimulants. To ensure safety, we avoided supplements with more than 400mg of caffeine per serving, the FDA-recommended daily intake limit.

Best Appetite Suppressants Customer Reviews

Our strongest appetite suppressant supplements have received mostly five-star ratings from satisfied customers.

Best Appetite Suppressants Cost

We scoured the internet for the best appetite suppressants without breaking your budget. At $84.99 for 30 pills, Phen24 is our most costly diet pill suggestion, though sometimes it is discounted to $69.99. Following Phen24 are PhenQ ($69.99), Instant Knockout ($65), Leanbean ($59.99), Zotrim ($49.99), Trimtone ($49.99) and PrimeShred ($49.99).

Best Appetite Suppressants Discounts

A discount is applied to all prices above except Instant Knockout and Leanbean. However, it is unclear if the price cuts are temporary or permanent. Save $10 on each of PhenQ, Phen24, and Trimtone; $20 on Zotrim; and $79.01 on PrimeShred for a 30-day supply.

Best Appetite Suppressants Refunds and Guarantees

You may buy with confidence since there are 100% money-back guarantees on everything we reviewed. They will give you your money back if you return unopened bottles.

With Instant Knockout, you only have 30 days to make a refund. It’s worth noting that both PhenQ and Phen24 come with 60-day money-back guarantees. Leanbean offers a warranty of up to 90 days on orders of 90 days’ worth of supplies or more. PrimeShred boasts the industry’s longest satisfaction guarantee at 365 days, although competitors Zotrim and Trimtone also offer 100-day money-back guarantees.

>>Check the latest deals for PhenQ

How To Take the Best Appetite Suppressant Pills

You may take the best appetite suppressants in a few different ways depending on the product you buy. 

How Long Should I Take the Best Appetite Suppressants?

The strongest appetite suppressant pill packaging will tell you to expect benefits in two to three months. However, some may state it will just be a few weeks. To guarantee positive outcomes, continue taking your chosen supplement for at least three months.

What Is the Best Time of Day to Take the Best Appetite Suppressants?

Taking a safe appetite suppressant before breakfast is optimal. The diet pills’ fiber content is most effective when taken with a full drink of water. That way, food may expand in your stomach, helping you feel full and reducing your appetite.

Taking two tablets of Leanbean three times a day and one pill of Phen24 twice a day (before breakfast and supper) represent the only exemptions on our list.

Best Appetite Suppressants Diet and Lifestyle Changes

When using diet pills, it is essential to complement them with a healthy eating plan and regular exercise. Supplements that reduce appetite are not intended to replace healthy eating with fast food, cakes and sweets or a sedentary lifestyle.

Best Appetite Suppressants: The Types 

There are two primary categories of the most potent appetite suppressant supplements available: those that are natural and those that are available by prescription only.

Naturally Safe Appetite Suppressant

Natural over-the-counter safe appetite suppressant supplements are comparable to the products we’ve highlighted in our guide to the best appetite suppressants for weight loss. They contain all-natural components, including glucomannan, guarana, caffeine, green coffee bean extract and cayenne pepper.

Prescription Safe Appetite Suppressant

Several drugs FDA-authorized can help you reduce hunger. Here are some of them:

  • Diethylpropion is a safe, prescription appetite-suppressant supplement and weight-loss aid, but you can only use it temporarily. It has a significant risk for addiction and might cause drowsiness.
  • You can take phentermine with a drug that relieves migraines and seizures in Qsymia (phentermine and topiramate). Topiramate is often prescribed to those looking to lose weight because it can reduce appetite, alter food flavor and increase metabolic rate. Since the phentermine dosage is reduced, it is FDA-approved for sustained usage.
  • Phendimetrazine is a safe appetite suppressant for both adolescents and adults. Addiction is possible with prolonged use (more than a couple of weeks).
  • Because of its amphetamine properties, the risk of addiction and severe adverse effects, you should use benzphetamine for no more than a few weeks.
  • Phentermine is an amphetamine, and its usage is limited to as little as 12 weeks before being discontinued due to concerns about dependency and other adverse effects.
  • An extended-release formulation of Contrave, which contains both naltrexone hydrochloride and bupropion, is a combination drug. Buprenorphine is used to treat depression and as a smoking cessation aid. In contrast, doctors prescribe naltrexone to treat opiate and alcohol addiction [15].
  • Saxenda (liraglutide), a higher-dosage medicine for diabetes, is administered. It works by imitating a hormone in the intestines that signals the brain that you are full. It may be used safely in kids as young as 12 years old. Saxenda is only accessible as an injection, not as a tablet.
  • Wegovy (semaglutide) is effective because it mimics a hormone in the intestine that increases insulin production, reducing hunger and making you feel full. The only way to take Wegovy is as a weekly injection.

>>Check the best prices for PhenQ

Are the Best Appetite Suppressant Supplements Safe for Everyone?

These supplements may not be safe appetite suppressants for all people. Pregnant women or nursing mothers should not take them because of the risk of adverse effects on the developing fetus. They’re also a potential danger to persons with disorders affecting the digestive system, the gallbladder, the heart, the endocrine system, or the mental state. 

In contrast, looking into other supplements to help you on your weight loss journey, such as the best probiotics or belly fat burners, might be ideal.

Best Appetite Suppressants Benefits

The best appetite suppressants work by reducing hunger, making it easier to stick to a calorie-restricted diet, and facilitating weight loss. Several diet pills on the market will give you the extra motivation you need to go to the gym and cook nutritious meals.

Even if your eating plan and workout routine are spot on, using the best appetite suppressant supplements may boost your metabolism, allowing you to burn fat more quickly.

Best Appetite Suppressants Potential Side Effects

Side effects are possible with every drug or supplement you take orally. Nausea, vomiting, diarrhea, rapid heart rate, high blood pressure, anxiety, nervousness, palpitations, fainting, lightheadedness, drowsiness, sleeplessness, bloating, gas and constipation are only some of the possible adverse reactions.

Best Appetite Suppressants Contraindications

The strongest appetite suppressant supplements include ingredients you should avoid during pregnancy and nursing.

People with diabetes, heart disease, liver disease, glaucoma and those struggling with mental health concerns should avoid some supplements. Specific drugs such as digoxin, lithium carbonate, or warfarin can interact negatively with these supplements.

>>Check the best deals for PhenQ

Best Appetite Suppressants Common FAQs

People have a lot of inquiries regarding which supplements are the best appetite suppressants. The following are examples of three of them.

What Safe Appetite Suppressant Supplements Works Best?

After extensive investigation, PhenQ was the most potent appetite suppressant supplement, as well as one of the best fat burners. However, different individuals will have various responses to certain supplements. For this reason, you’ll need to find the one that works best for you, in addition to a healthy diet and regular exercise.

Is There a Pill I Can Take to Suppress My Appetite?

Several strongest appetite suppressant supplements are available, both by prescription and over the counter, that you may use to help you eat less.

If you have a doctor’s prescription, you may use weight loss pills such as phendimetrazine, Contrave, phentermine, Qsymia, diethylpropion, or benzphetamine. There are many more than the hundred described in this guide regarding natural appetite suppressants.

What Is a Good Over the Counter Safe Appetite Suppressant Supplements?

After extensive study, we have concluded that the best appetite suppressants you can purchase over the counter are PhenQ, Instant Knockout, Leanbean, Zotrim, Phen24, Trimtone and PrimeShred.

Is Coffee An Appetite Suppressant?

Caffeine has been known as an appetite suppressor, but there are also reports indicating that it could stimulate appetite [16]. Relying on coffee alone won’t be a successful method for losing weight.

>>Check the latest prices for PhenQ

Our Best Appetite Suppressants Ranking Methodology Explained

Efficacy, ingredient safety, affordability and user happiness were among the many factors we considered while ranking these natural appetite-suppressing supplements.

We gave them a score between one and five, with five being the highest possible rating. 

Best Appetite Suppressants Efficacy

All of the most potent appetite suppressant supplements we tested were evaluated based on their ability to provide the promised benefits to the end user. Every weight loss product works best when used in tandem with an active lifestyle and a balanced diet. We analyzed the effects of each supplement’s component on weight loss, then gathered feedback from customers to conclude effectiveness.

Best Appetite Suppressants Ingredient Safety

We analyzed each product’s components to help you choose the most potent appetite-suppressant supplement while also ensuring its safety.

Most substances are harmless in the absence of a known allergy or sensitivity. We extensively studied the few substances that may cause problems if you take more than the manufacturer’s advised amount. To our knowledge, the amounts used in each strongest appetite suppressant supplements are safe.

Best Appetite Suppressants Cost

Price tags are meaningless when discussing the benefits of improved health and increased vitality of losing weight. Still, we did our best to provide you with various price plans. Multiple pricing points are available for the most potent appetite suppressant tablets.

Best Appetite Suppressants User Satisfaction

Consumer happiness ranks high on our list of priorities. We wouldn’t promote one of the most potent appetite suppressant supplements if consumers were unified in their disapproval of the product.

Best Appetite Suppressants: The Verdict

We’ve compiled a list of the seven strongest appetite suppressant supplements available today and presented them here. 

It’s important to carefully examine your options before committing to a weight loss pill. You can also research prior purchasers’ comments and seek medical advice if unsure of what to choose. That said, explore your options to get the most potent appetite-suppressant supplements for your needs.

We recommend combining the most potent appetite suppressant supplements like PhenQ with a low-calorie diet and regular exercise for maximum efficacy. 

>>Check the best prices for PhenQ

Related articles:


  1. Staff, the Premerger Notification Office, and This blog is a collaboration between CTO and DPIP staff and the AI Strategy team. “Commercial Weight Loss Products and Programs What Consumers Stand to Gain and Lose.” Federal Trade Commission, 5 Aug. 2021.
  2. Anton, Stephen D, et al. “Effects of Chromium Picolinate on Food Intake and Satiety.” Diabetes Technology & Therapeutics, Mary Ann Liebert, Inc., Oct. 2008.
  3. “Phenq Is Rated ‘Average’ with 3.6 / 5 on Trustpilot.” Trustpilot, 30 Dec. 1969.
  4. Zheng J, Zheng S, Feng Q, Zhang Q, Xiao X. Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications. Biosci Rep. 2017 May 11;37(3):BSR20170286. doi: 10.1042/BSR20170286. PMID: 28424369; PMCID: PMC5426284.
  5. “Instant Knockout Fat Burner Is Rated ‘Average’ with 3.4 / 5 on Trustpilot.” Trustpilot,
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  8. Ruxton, C.H.S., et al. “Effectiveness of a Herbal Supplement (Zotrim™) for Weight Management.” British Food Journal, Emerald Publishing Limited, 19 June 2007.
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  10. Zheng J, Zheng S, Feng Q, Zhang Q, Xiao X. Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications. Biosci Rep. 2017 May 11;37(3):BSR20170286. doi: 10.1042/BSR20170286. PMID: 28424369; PMCID: PMC5426284.
  11. Hodgson AB, Randell RK, Jeukendrup AE. The effect of green tea extract on fat oxidation at rest and during exercise: evidence of efficacy and proposed mechanisms. Adv Nutr. 2013 Mar 1;4(2):129-40. doi: 10.3945/an.112.003269. PMID: 23493529; PMCID: PMC3649093.
  12. Sugita, Jun et al. “Daily ingestion of grains of paradise (Aframomum melegueta) extract increases whole-body energy expenditure and decreases visceral fat in humans.” Journal of nutritional science and vitaminology vol. 60,1 (2014): 22-7. doi:10.3177/jnsv.60.22
  13. Dimethylethanolamine (DMAE) [108-01-0] and Selected Salts …
  14. Fernández-Lázaro D, Mielgo-Ayuso J, Córdova Martínez A, Seco-Calvo J. Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (Bioperine®) and Potential Applications. Nutrients. 2020 Jun 24;12(6):1886. doi: 10.3390/nu12061886. PMID: 32599787; PMCID: PMC7353321.
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The opinions in this article do not necessarily reflect the opinions of the Las Vegas Review-Journal and you should consult your doctor before beginning any new health related practice.

Members of the editorial and news staff of the Las Vegas Review-Journal were not involved in the creation of this content.


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