November 28, 2023

The bodyweight loss drug Wegovy has been in the headlines this month. Listed here, our Head of Care Douglas Twenefour clarifies the principal factors to be conscious of with Wegovy, like who it is advisable for and how it functions.

Douglas Twenefour

What is Wegovy? 

Wegovy is a model name for semaglutide, a GLP-1 analogue. It is a body weight decline drug created by Danish pharmaceutical organization Novo Nordisk. 

When Wegovy has not yet been introduced in the British isles, and we do not know when it will be launched, the Nationwide Institute for Wellbeing and Care Excellence (Wonderful) issued draft direction in February 2022 recommending Wegovy be approved to men and women who have a individual BMI (commonly 35kg/m2 and more than) and at the very least 1 bodyweight-linked health and fitness condition. 

The moment launched in the British isles, Wegovy could be approved to people today with prediabetes or kind 2 diabetes as an alternative for pounds administration inside a specialist pounds administration provider. This will depend on a person’s own conditions, and aspects these as their current cure plan and danger of aspect outcomes.  

Semaglutide is also accredited underneath the manufacturer names Ozempic and Rybelsus, which are suggested by Great and offered on the NHS for running blood glucose levels in folks with style 2 diabetes.  

What are the discrepancies between the distinct semaglutide model names? 

  • Ozempic and Rybelsus (pill) are advised to control blood glucose in people today with sort 2 diabetes.  
  • Wegovy is advised for bodyweight administration in individuals with or without the need of kind 2 diabetic issues. 
  • Ozempic and Rybelsus have been released and offered in the United kingdom, even though there are presently some provide troubles with Ozempic.  
  • Wegovy is nevertheless to be launched in the United kingdom.  
  • Equally Ozempic and Wegovy are injectables, with Wegovy coming in higher doses than Ozempic.
  • Rybelsus is a tablet so straight comparing its doses to the other two makes is not as straightforward.

Wegovy and pounds loss 

Wegovy can guide to weight loss since it is designed to suppress urge for food so you try to eat significantly less. It mimicks the motion of a intestine hormone named GLP-1, which is launched following having, and it slows down the motion of foods in your gut so you keep full for for a longer period.

The quantity of bodyweight you shed on Wegovy would count on your personalized situation, the assistance you acquire and how lengthy you are on the treatment for.  

In a big examine, the Stage 1 scientific demo, people today on the utmost dose shed 12% much more of their entire body body weight in comparison to these who were being not on the medicine. Crucially, both groups obtained assistance to reduce their calorie intake, and improve their actual physical action ranges, which shows the relevance of producing individuals changes to get the greatest out of any excess weight decline remedies. 

Like other pounds reduction remedies, there is proof of excess weight regain when people today halt employing Wegovy so it is significant to proceed earning variations to your diet and bodily activity amounts. 

Does Wegovy have side effects? 

Nausea is a frequent aspect result when first beginning Wegovy, while other aspect outcomes can involve constipation and diarrhoea. 

When Wegovy will become accessible, extra info about the side effects will be contained in the Affected individual Information and facts Leaflet (PIL) which will come in the box of the treatment.   

It is essential that a man or woman can take specific advice from their healthcare team just before beginning a new prescription of Wegovy, and stories any side outcomes. 

What need to I do if I want to be approved weight decline treatment? 

Some blood glucose lowering medications for men and women with variety 2 diabetes these as GLP-1 analogues and SGLT2 inhibitors can guide to pounds reduction, but these are not body weight decline medicines. 

There are at this time two fat loss prescription drugs out there on the NHS: Xenical (generic identify Orlistat) which is a capsule, tablet, and Saxenda which is a brand name for liraglutide, a kind of GLP-1 analogue that is injected every day.  

Orlistat will work by limiting the volume of extra fat your entire body absorbs from the food you consume. There is an additional model identify for Orlistat which is called alli and this can be purchased with no prescription. 

It is vital to speak to your GP, nurse or dietitian to talk about pounds management solutions, which include pounds decline treatment, that might be helpful for you. 

Far more information and assistance  

  • Ring our helpline with any questions or problems on 0345 123 2399 
  • Learn additional about managing diabetes with tablets and treatment.


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