November 28, 2023

WeightWatchers’ inventory soared on Tuesday immediately after the corporation stated it is acquiring into the prescription drug bodyweight loss business enterprise with the acquisition of Sequence.

Sequence is a telehealth supplier that presents buyers obtain to medication used to take care of diabetic issues and obesity underneath these types of brand names as Ozempic, Wegovy and Trulicity.

The medicines all perform by the exact same mechanism: They trigger the launch of insulin, block sugar output in the liver and suppress urge for food.

WeightWatchers provides subscribers meal designs with the goal of shedding excess fat. With the acquisition of Sequence, it is tapping into a purple-very hot current market for prescription medicine that deal with obesity and broadening what it offers to prospects.

“It is our responsibility, as the trustworthy leader in fat management, to aid these fascinated in exploring if drugs are appropriate for them,” CEO Sima Sistani stated in a ready assertion late Monday.

Observe | Thoughts swirl all over use of Ozempic for weight loss: 

Ozempic for bodyweight loss: What is recognised about the probable and the challenges

Queries are swirling around the use of semaglutide, frequently offered less than the model identify Ozempic, for weight loss. CBC’s Christine Birak explores the hazards and rewards of off-label works by using of the drug, which is ordinarily utilized to handle Sort 2 diabetes.

What are Ozempic and Wegovy?

Ozempic and Wegovy are distinct versions of the exact same drug, recognised as semaglutide.

They are each presented as the moment-weekly injections. Ozempic is authorised only to handle diabetic issues, whilst it has been more and more recommended for off-label use.

Wegovy was permitted in 2021 to handle weight problems in grown ups, and late very last yr to take care of the ailment in adolescents 12 and more mature. In a clinical demo, adults who utilized Wegovy shed about 15 per cent of their original system body weight, when teens dropped a bit a lot more.

A long, white box, with the word Ozempic written in blue on the front side, sits on top of a blue cylinder.
The anti-diabetic medicine Ozempic (semaglutide), created by pharmaceutical company Novo Nordisk, is demonstrated in Paris on Feb. 23. The off-label use of semaglutide led to a shortage for most of 2022. Novo Nordisk claimed provides are getting replenished, but quite a few diabetes sufferers are even now unable to entry the drug. (Joel Saget/AFP/Getty Images)

For ideal outcomes, the medications need to be mixed with diet program and exercising, specialists say. Trulicity is a distinct drug, dulaglutide, made use of to address diabetic issues in grownups and children ages 10 and older. It’s not permitted to take care of obesity.

The off-label use of semaglutide, spurred by social media posts, led to a lack of the drug for most of very last calendar year. Novo Nordisk reported provides are remaining replenished, but several diabetic issues sufferers even now report issues accessing the drugs they need.

Each Ozempic and Wegovy can induce achievable facet-consequences, the enterprise experiences. They include things like attainable thyroid most cancers, pancreatitis, and kidney and gallbladder troubles.

The most popular aspect-effects are nausea, vomiting, diarrhea, belly ache and constipation. Weight problems prevalence rose from 30.5 per cent from the 1999-2000 interval to 41.9 per cent for 2017 by means of March 2020, according to the U.S. Centers for Illness Command and Avoidance (CDC). The prevalence of serious obesity surged from 4.7 for every cent to 9.2 per cent for the similar intervals.

At the moment, Wegovy and Saxenda are permitted drugs for being overweight in the United States, with tirzepatide also extensively expected to be authorised for it later on this 12 months.

In December, Eli Lilly CEO David Ricks identified as the drug a person of its “generational chances.” The drug was very last calendar year authorized for diabetes, for which it is sold less than the brand Mounjaro.

Pay attention | Diabetic issues, obesity professional shares what you must know about Ozempic: 

The Dose17:26Why is Ozempic receiving so a lot notice?

We’ve been hearing a large amount about Ozempic not too long ago. It is a drug to address diabetes, but it’s now getting to be well-liked with stars and typical individuals seeking to shed a few lbs .. Dr. Ali Zentner, a Vancouver-primarily based expert in internal medicine, diabetic issues and obesity, shares what you really should know about the drug.

High price of being overweight

The approximated annual health-related value of weight problems in the United States was practically $173 billion US in 2019 bucks, according to the CDC.

Once-a-year health-related expenditures for grown ups who had been obese were $1,861 bigger than professional medical fees for persons with a healthy bodyweight.

“This deal brings access to prescription drug methods for body weight loss to WW’s historical target on conduct modification model,” wrote UBS analyst Michael Lasser.

“This is a important improve in the business enterprise. Even though the offer could deliver appreciable upside, it also carries sizable risks.” Lasser stated that WW’s organization has been disrupted around the very last several a long time and is now making an attempt to just take big methods to training course suitable.

“We assume it will get time to see if this motion truly produces a modify in the firm’s fortunes,” he said. WW Intercontinental, primarily based in New York, will shell out $106 million for Sequence, which served about 24,000 users across the U.S. as of February, with annual earnings of about $25 million. The acquisition is anticipated to shut in the fiscal next quarter.

Shares of WW International Inc. closed Tuesday up 79 per cent.

Observe | Ozempic’s acceptance surges on TikTok: 

Ozempic: TikTok’s fixation and the diet regime lifestyle cycle

Jan. 19, 2023 | Ozempic, a drug utilised to support address Type 2 diabetes, has soared in popularity thanks to a facet-outcome — urge for food suppression. Andrew Chang explores how movie star weight loss, diet program society and social media have even further fueled the demand from customers.

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