December 9, 2023

Crucial Takeaways

  • Some individuals who use diabetes medications like Ozempic and Wegovy for weight reduction have reportedly found facial growing old and sagging.
  • A New York-centered skin doctor referred to this type of skin sagging due to quick weight loss as “Ozempic facial area.”
  • Professionals say this phenomenon is widespread among the clients who drop too much body weight much too swiftly.

Although variety 2 diabetic issues drugs like Ozempic (semaglutide) are nonetheless in high demand for speedy fat reduction, more end users are noticing an unwelcome aspect impact: the “Ozempic experience.”

This time period, coined by New York-primarily based skin doctor Paul Jarrod Frank, MD, refers to the facial growing old and sagging that some Ozempic customers have expert.

What Is Ozempic Employed For?

Ozempic is a prescription injection that is Fda-approved for taking care of blood sugar degree in grown ups with style 2 diabetic issues. The Fda has not approved Ozempic for pounds loss, but some companies could prescribe the drug for off-label use.

Steven Heymsfield, MD, a professor whose investigation focuses on being overweight and bodyweight reduction treatment method at Pennington Biomedical Investigation Middle in Baton Rouge, La., said the term “Ozempic face” is deceptive.

“It’s a side influence of all bodyweight reduction, it is very little exclusive to Ozempic that I’m informed of,” Heymsfield informed Verywell.

Fast body weight loss can direct to sagging pores and skin and stretch marks on other parts of the body much too, not just the facial area. “When people eliminate body weight, they eliminate it everywhere,” he mentioned. “People are talking about Ozempic deal with for the reason that you can see it.”

Just one review confirmed that people who had a weekly injection of semaglutide, the active ingredient Ozempic, misplaced an ordinary of practically 15% by week 68.

Ozempic experience is a cosmetic side effect that some individuals have treated with fillers, but it is also preventable by slowing down pounds loss, Heymsfield additional.

“What that tells us is that additional than most likely, folks are not making use of this drug as recommended on the label by the Food and drug administration,” he said.

Is Ozempic Encounter Preventable?

Gradual body weight decline can assistance prevent sagging pores and skin, but gurus say that diet program and exercise also enjoy a position in tightening the skin.

Rocio Salas-Whalen, MD, a double board-qualified medical professional specializing in obesity, diabetic issues, and thyroid disorders, claimed she endorses increasing protein intake all through the bodyweight-loss procedure to build collagen and elastin, which help with skin elasticity.

She extra that clients applying Ozempic or a very similar drug must consume 1-2 liters of h2o each and every working day to continue to be hydrated. “These drugs can bring about dehydration,” she reported. “When the pores and skin is dry from dehydration, it is more susceptible to wrinkles and loss of elasticity.”

Creating muscle groups by way of resistance training can also enable tighten skin on specified components of the overall body, but this likely will not stop Ozempic encounter.

What Are the Other Side Results of Ozempic?

Sagging pores and skin may well be one particular cosmetic side influence of fast pounds decline, but industry experts say there are other facet consequences to take into consideration when having Ozempic or Wegovy, a comparable diabetic issues drug that was approved by the Food and drug administration for chronic bodyweight administration in 2021.

The two Ozempic and Wegovy belong to a course of medications identified as GLP-1 receptor agonists and had been at first made to deal with type-2 diabetic issues by promoting insulin manufacturing after a food.

“GLP-1 agonists impact gastric motility, and that signifies that men and women will have nausea and vomiting and they may perhaps have some reflux,” Heymsfield said.

Nausea can be managed by setting up up a tolerance to the drug and increasing doses progressively, but individuals on the lookout for a “magic bullet” do not usually want to start at the cheapest dose, he spelled out.

Wegovy arrives in five doses ranging from .25 mg to 2.4 mg. According to Wegovy’s website, people need to raise doses each four months. Sufferers who follow this plan would not attain the entire 2.4 mg dose right up until 7 days 17.

Heymsfield explained patients typically question him to start off at the highest dose, but he’d suggest them to “go gradual, try to eat a healthier diet regime, and change your approaches. You’ll almost certainly be a ton far better off in the extended operate.”

Whilst some men and women are spending hundreds of dollars a thirty day period to get these medication off-label for immediate body weight loss, loads of men and women are making use of Wegovy and Ozempic as intended to deal with persistent conditions.

For people with type 2 diabetic issues, there is a danger of establishing lower blood sugar, or hypoglycemia, when taking these medications together with insulin. There is also some evidence to suggest that these drugs may well lead to uncommon side effects, these kinds of as pancreatitis, gallstones, and kidney failure.

“I think that the majority of people today that are on these medicines actually profit health and fitness-smart from them,” Salas-Whalen explained, “The skills of their prescriber is key in the achievement and to limit the facet outcomes of the medication.”

What This Means For You

“Ozempic deal with” refers to the sagging of skin owing to rapid weight loss. Experts say it can be preventable by slowing down weight loss, being hydrated, and rising protein ingestion.

Correction – February 6, 2023: A earlier edition of this short article misstated an old affiliation of Rocio Salas-Whalen, MD. This post has been up-to-date to reflect her most recent title.


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